Purpose: EndoArt, a synthetic endothelial substitute for corneal edema, often requires multiple rebubbling procedures because of high detachment rates. This study reports 2 cases of spontaneous EndoArt reattachment, suggesting a potential alternative management approach.
Methods: Two patients with endothelial dysfunction underwent EndoArt implantation. Both experienced partial detachment postoperatively. Although rebubbling was considered, a conservative approach was taken, leading to spontaneous reattachment. Serial anterior segment optical coherence tomography (AS-OCT) monitored graft adherence and corneal thickness.
Results: Spontaneous reattachment occurred within 2 to 6 weeks, accompanied by progressive corneal thinning and clarity improvement. No further intervention was required, and reattachment remained stable for 6 to 8 months. These cases challenge the notion that all EndoArt detachments necessitate immediate rebubbling.
Conclusions: This is the first report of spontaneous EndoArt reattachment. Although rebubbling remains standard practice, observation may be a viable option in select cases, reducing the need for additional procedures. Further studies are needed to refine management strategies and improve outcomes.
Keywords: EndoArt; artificial endothelial graft; bullous keratopathy; endothelial dysfunction.
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