Anesthetic Efficacy, Injection Pain and Pulse-rate Effect of Needle-free Injection in Pulpal Anesthesia of Maxillary Premolars with Irreversible Pulpitis: Randomised Clinical Study

Eur Endod J. 2025 May;10(3):181-187. doi: 10.14744/eej.2025.26566.

Abstract

Objective: This study aims to compare the pain perception associated with the needle-free system (Comfort-In™) and the standard needle injection method during root canal treatments in adults.

Methods: Forty-four maxillary premolar teeth of the patients that applied to university for treatment and needed endodontic treatment were included in the study. Patients were anesthetized with two different injection methods; needle-free injection and conventional dental injection. In both groups, oxygen saturation and pulse measurements of the patients were recorded at 30-second intervals for 2 minutes before anesthesia and 4 minutes after anesthesia. Pain during the injection and opening of the access cavity preparation was recorded according to Visual Analog Scale (VAS). The data were analyzed according to a statistical program.

Results: In this study, a significant difference was found between the groups in terms of pain during anesthesia administration and the access cavity preparation (p<0.001). There were no significant differences in terms of gender and age (p>0.05). There was no significant difference between the groups in terms of oxygen saturation and pulse values before and after treatment (p>0.05).

Conclusion: Needle-free injection makes the treatment more comfortable for patients with injection fear and anxiety, making the procedure easier for the physician and the patient. (EEJ-2024-12-197).

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Anesthesia, Dental* / methods
  • Anesthetics, Local* / administration & dosage
  • Bicuspid*
  • Female
  • Heart Rate*
  • Humans
  • Injections* / adverse effects
  • Injections* / methods
  • Male
  • Maxilla
  • Needles
  • Pain Measurement
  • Pain* / etiology
  • Pulpitis* / therapy
  • Root Canal Therapy / methods
  • Young Adult

Substances

  • Anesthetics, Local