The complex role of brain cilia in feeding control

Science. 2025 Jun 5;388(6751):1026-1027. doi: 10.1126/science.ady6368. Epub 2025 Jun 5.

Abstract

Variants in a ciliary receptor are associated with obesity.

Publication types

  • Comment

MeSH terms

  • Animals
  • Appetite Regulation* / genetics
  • Brain* / physiology
  • Cilia* / physiology
  • Humans
  • Mice
  • Obesity* / genetics
  • Obesity* / physiopathology
  • Receptors, G-Protein-Coupled* / genetics
  • Receptors, G-Protein-Coupled* / metabolism
  • Smoothened Receptor

Substances

  • Receptors, G-Protein-Coupled
  • Smoothened Receptor