Clostridioides difficile-infeksjon

Tidsskr Nor Laegeforen. 2025 Jun 2;145(7). doi: 10.4045/tidsskr.24.0233. Print 2025 Jun 3.
[Article in Norwegian]

Abstract

This clinical review examines the epidemiology, diagnosis and treatment of Clostridioides difficile infection, a feared cause of diarrhoea following use of antibiotics. A third of cases are diagnosed outside the hospital setting, and one in four patients experience a relapse despite seemingly successful treatment. Norwegian and international guidelines have recently updated their recommendations on antibiotic choices for primary infection. Doctors both in hospitals and outside the hospital setting should be familiar with risk factors, diagnostics and treatment principles.

Publication types

  • Review
  • English Abstract

MeSH terms

  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / adverse effects
  • Anti-Bacterial Agents / therapeutic use
  • Clostridioides difficile* / isolation & purification
  • Clostridium Infections* / diagnosis
  • Clostridium Infections* / drug therapy
  • Clostridium Infections* / epidemiology
  • Clostridium Infections* / microbiology
  • Diarrhea / drug therapy
  • Diarrhea / microbiology
  • Humans
  • Norway / epidemiology
  • Practice Guidelines as Topic
  • Risk Factors

Substances

  • Anti-Bacterial Agents