[Comparison of oral administration and intramuscular injection of thymus preparations on the leukopoiesis test in rats and some of the preventive possibilities emerging from the results]

Z Alternsforsch. Jul-Aug 1985;40(4):225-34.
[Article in German]


Considering the fact that all immunologic processes consume energy, we have been attempting for more than a decade to combine immunostimulating measures with such for increasing the energetic state. This basic resulted in designing several modern variants of the Oxygen Multistep Immunostimulation. In order to make this method broadly applicable to public health care, its protocol had to be simplified in such a way that it can easily be applied also to outpatients at a reasonable expenditure of time. Such a program is described here among other variants. Its concept is based on measurements of leukopoiesis in rats after administration of thymus extract. The test system used revealed that oral administration of the thymus extract taken from specified dragées was of at least the same effect as intramuscular injection. The simplified variant of the Oxygen Multistep Immunostimulation which can be practised ambulantly within a short time, consists of the administration of thymus dragées and the 15-min-oxygen multistep quick procedure of the Oxygen Multistep Therapy. It is demonstrated by comparison of photographs of a case report the precancerous skin lesions can be unprimed by this simple treatment within 10 months. The finding indicates that along these lines a permanently effective cancer prevention might become practicable. Furthermore, it is supposed that the simple treatment schedule described should be of benefit in preventive medicine and gerontology as well, in order to fight illness in general and to reduce the disposition to diseases having a bad prognosis particularly in old age.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Administration, Oral
  • Adult
  • Aged
  • Animals
  • Combined Modality Therapy
  • Humans
  • Immunotherapy
  • Injections, Intramuscular
  • Leukocytes / drug effects*
  • Leukocytes / immunology
  • Male
  • Middle Aged
  • Oxygen Inhalation Therapy
  • Precancerous Conditions / therapy
  • Rats
  • Rats, Inbred Strains
  • Skin Neoplasms / therapy
  • Thymus Extracts / administration & dosage*


  • Thymus Extracts