Renal Denervation: Patient Selection and When to Refer

Am J Cardiol. 2025 Oct 1:252:88-92. doi: 10.1016/j.amjcard.2025.06.009. Epub 2025 Jun 9.

Abstract

The US FDA approved Renal Denervation for hypertension treatment in November 2023. Regardless of the methodology used to denervate, most but not all people had a clinically significant reduction in blood pressure in the months following the procedure. In this review we summarize the current data informing patient selection, and provide guidance on when to refer potential patients for consideration of this therapy in the management of uncontrolled hypertension.

Keywords: hypertension; patient referral; patient selection; renal denervation.

Publication types

  • Review

MeSH terms

  • Blood Pressure / physiology
  • Humans
  • Hypertension* / physiopathology
  • Hypertension* / surgery
  • Kidney* / innervation
  • Patient Selection*
  • Referral and Consultation*
  • Sympathectomy* / methods