Lemmel Syndrome Detected on 99m Tc-Mebrofenin Hepatobiliary Scintigraphy

Dhananjaya Saraswat; Pareena Malik; Suraj Kumar; Aakash Sethi; Govindasamy Sundareshan; Usha Dutta; Bhagwant Rai Mittal; Anish Bhattacharya

doi:10.1097/RLU.0000000000005736

Lemmel Syndrome Detected on 99m Tc-Mebrofenin Hepatobiliary Scintigraphy

Clin Nucl Med. 2025 Aug 1;50(8):e509-e511. doi: 10.1097/RLU.0000000000005736. Epub 2025 Jun 17.

Authors

Dhananjaya Saraswat¹, Pareena Malik¹, Suraj Kumar¹, Aakash Sethi², Govindasamy Sundareshan², Usha Dutta³, Bhagwant Rai Mittal¹, Anish Bhattacharya¹

Affiliations

¹ Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
² Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
³ Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

PMID: 40524362
DOI: 10.1097/RLU.0000000000005736

Abstract

Lemmel syndrome is a rare clinical condition characterized by cholestatic jaundice caused by compression of the common bile duct (CBD) by a periampullary duodenal diverticulum. The authors present a patient with post-cholecystectomy jaundice, in whom 99m Tc-Mebrofenin hepatobiliary scintigraphy showed pooling of tracer activity in the proximal CBD with delayed bilioenteric drainage. Single photon emission computed tomography/computed tomography detected a duodenal diverticulum medially displacing and compressing the distal CBD, which was corroborated by magnetic resonance cholangiopancreatography.

Keywords: HIDA; Lemmel syndrome; mebrofenin.

Publication types

Case Reports

MeSH terms

Aniline Compounds
Biliary Tract* / diagnostic imaging
Glycine
Humans
Imino Acids*
Liver* / diagnostic imaging
Organotechnetium Compounds*
Radionuclide Imaging
Syndrome

Substances

Aniline Compounds
Imino Acids
Organotechnetium Compounds
technetium Tc 99m mebrofenin
Glycine