Rare recombination in Salix nivalis and the maintenance of homomorphic sex chromosomes in willows

Am J Bot. 2025 Jun;112(6):e70059. doi: 10.1002/ajb2.70059. Epub 2025 Jun 17.

Abstract

Premise: Most dioecious angiosperms have homomorphic sex chromosomes, and non-recombining sex-linked regions (SLRs) likely comprise a small portion of the sex chromosome. The fountain of youth hypothesis posits that rare recombination within heterogametic SLRs may act to maintain homomorphy. Alternatively, turnovers of the sex-determining genes could also contribute to sex chromosome homomorphy.

Methods: We used reduced representation sequencing and mapping to the Salix purpurea reference genome to determine the size of the sex-linked region in three dwarf willows (Salix phlebophylla, S. reticulata, and S. nivalis). To test the fountain of youth hypotheses, we performed allelic state and linkage disequilibrium (LD) analyses.

Results: For all three species, sex-linked single nucleotide polymorphisms (SNPs) were identified on chromosome 15. Mean heterozygosity was higher in females, confirming that all three species were female heterogametic (ZW). A recombinant haplotype between the Z and W chromosomes was identified in S. nivalis, contributing to higher-than-expected mean heterozygosity in SLR and slow LD decay in males.

Conclusions: We propose that the uncommon ZW haplotype resulting from a recombination event identified here initiates the homogenization of Z and W chromosomes, leading to the maintenance of their homomorphy. Based on comparisons across all three SLRs, we further speculate that ongoing rare recombination events have influenced the shared patterns of sex-linked SNPs across S. phlebophylla, S. reticulata, and S. nivalis and is a process that influences sex chromosome evolution throughout the Salicaceae and flowering plants with homomorphic sex chromosomes.

Keywords: Salicaceae; dwarf willows; recombination; sex chromosomes; sex‐linked regions.

MeSH terms

  • Chromosome Mapping
  • Chromosomes, Plant* / genetics
  • Haplotypes
  • Linkage Disequilibrium
  • Polymorphism, Single Nucleotide / genetics
  • Recombination, Genetic*
  • Salix* / genetics
  • Sex Chromosomes* / genetics