The genome sequence of the common hop, Humulus lupulus L

Maarten J M Christenhusz; Lawrence Percival-Alwyn; Klara Hajdu; John Connell; Ilia J Leitch; Royal Botanic Gardens Kew Genome Acquisition Lab; Darwin Tree of Life Barcoding collective; Plant Genome Sizing collective; Wellcome Sanger Institute Tree of Life Management, Samples and Laboratory team; Wellcome Sanger Institute Scientific Operations: Sequencing Operations; Wellcome Sanger Institute Tree of Life Core Informatics team; Tree of Life Core Informatics collective; Darwin Tree of Life Consortium

doi:10.12688/wellcomeopenres.24025.1

The genome sequence of the common hop, Humulus lupulus L

Wellcome Open Res. 2025 Apr 23:10:210. doi: 10.12688/wellcomeopenres.24025.1. eCollection 2025.

Authors

Maarten J M Christenhusz^{1

2}, Lawrence Percival-Alwyn³, Klara Hajdu⁴, John Connell³, Ilia J Leitch¹; Royal Botanic Gardens Kew Genome Acquisition Lab; Darwin Tree of Life Barcoding collective; Plant Genome Sizing collective; Wellcome Sanger Institute Tree of Life Management, Samples and Laboratory team; Wellcome Sanger Institute Scientific Operations: Sequencing Operations; Wellcome Sanger Institute Tree of Life Core Informatics team; Tree of Life Core Informatics collective; Darwin Tree of Life Consortium

Affiliations

¹ Royal Botanic Gardens Kew, Richmond, England, UK.
² Curtin University, Perth, Western Australia, Australia.
³ National Institute of Agricultural Botany, Cambridge, England, UK.
⁴ Wye Hops, Canterbury, England, UK.

Abstract

We present a genome assembly from a female Humulus lupulus plant (Common hop, Hops; Streptophyta; Magnoliopsida; Rosales; Cannabaceae). The genome sequence has a total length of 2,488.10 megabases. Most of the assembly (99.39%) is scaffolded into 10 chromosomal pseudomolecules, including the X sex chromosome. The mitochondrial and plastid genome assemblies have lengths of 400.02 kilobases and 153.77 kilobases, respectively. Gene annotation of this assembly by Ensembl identified 32,487 protein-coding genes.

Keywords: Common hop; Hops; Humulus lupulus; Rosales; chromosomal; genome sequence.