Reading the DNA of telomeres

Elife. 2025 Jun 18:14:e107648. doi: 10.7554/eLife.107648.

Abstract

Experiments with tools designed to detect DNA damage reveal unique and conserved features of telomeres in cancer cells.

Keywords: END-seq; alternative lengthening of telomeres; cancer; cancer biology; chromosomes; dsDNA; gene expression; human; mouse; ssDNA; telomeres.

Publication types

  • Editorial

MeSH terms

  • DNA Damage*
  • DNA* / genetics
  • DNA* / metabolism
  • Humans
  • Neoplasms / genetics
  • Telomere* / genetics
  • Telomere* / metabolism

Substances

  • DNA