Abstract
Seventeen monoclonal antibodies (MAs) were tested. Five of seven serovar-specific MAs from five different serovars and two of five subspecies-specific MAs showed neutralizing activity as well as serovar specificity. No species- or genus-specific MAs showed neutralizing activity. No neutralization occurred without complement. Results indicate neutralization was serovar specific and complement dependent.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Antibodies, Monoclonal*
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Antigens, Bacterial / immunology
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Chlamydia trachomatis / growth & development
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Chlamydia trachomatis / immunology*
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Cross Reactions
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HeLa Cells
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Humans
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Hybridomas / immunology
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Mice
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Species Specificity
Substances
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Antibodies, Monoclonal
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Antigens, Bacterial