The distribution and acyl composition of plasmalogens in guinea pig heart

Lipids. 1985 Oct;20(10):693-8. doi: 10.1007/BF02534389.


In guinea pig heart homogenate, 34% of both choline and ethanolamine phosphoglycerides were in the form of plasmalogens (1-alkenyl, 2-acyl glycerophospholipid). Plasmalogens accounted for 39% of the choline phosphoglycerides and 36% of the ethanolamine phosphoglycerides in the mitochondrial fraction. Ethanolamine plasmalogen was the major ethanolamine phosphoglyceride (63%) in the guinea pig heart microsomal fraction. A high arachidonyl content was found in both diacyl and 1-alkenyl, 2-acyl glycerophosphoethanolamine. The C-2 fatty acyl profiles of the diacyl and 1-alkenyl, 2-acyl choline phosphoglycerides differed considerably from each other in the homogenate as well as in the subcellular fractions. Significant differences in the C-2 fatty acyl profiles also were observed in diacyl and 1-alkenyl, 2-acyl ethanolamine phosphoglycerides. Such differences suggest there is no direct metabolic relationship between the diacyl glycerophosphocholine (-ethanolamine) and its plasmalogen analog.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acylation
  • Animals
  • Guinea Pigs
  • Male
  • Microsomes / analysis
  • Mitochondria, Heart / analysis
  • Myocardium / analysis*
  • Phosphatidylcholines / analysis
  • Phosphatidylethanolamines / analysis
  • Plasmalogens / isolation & purification*
  • Subcellular Fractions / analysis


  • Phosphatidylcholines
  • Phosphatidylethanolamines
  • Plasmalogens