In acute episodic migraine attacks, triptans, with or without NSAIDs, vs. NSAIDs alone reduce pain at 2 h and up to 48 h

Ann Intern Med. 2025 Jul;178(7):JC75. doi: 10.7326/ANNALS-25-02421-JC. Epub 2025 Jul 1.

Authors

John R Absher¹; ACP Journal Club Editorial Team at McMaster University

Affiliation

¹ Prisma Health, University of South Carolina, and Clemson University, Greenville, South Carolina, USA (J.R.A.).

PMID: 40587859
DOI: 10.7326/ANNALS-25-02421-JC

Abstract

GIM/FP/GP: [Formula: see text] Neurology: [Formula: see text].

MeSH terms

Acute Disease
Adult
Anti-Inflammatory Agents, Non-Steroidal* / therapeutic use
Drug Therapy, Combination
Female
Humans
Male
Middle Aged
Migraine Disorders* / drug therapy
Tryptamines* / therapeutic use

Substances

Tryptamines
Anti-Inflammatory Agents, Non-Steroidal