Selenium enhances salt tolerance in safflower via biochemical and molecular modulation

Sci Rep. 2025 Jul 1;15(1):21453. doi: 10.1038/s41598-025-07108-0.

Abstract

Salinity represents a significant challenge to global agriculture and crop production, emphasizing the need for innovative strategies to enhance the salt tolerance of various crop species. Selenium (Se), an essential inorganic plant elicitor, has shown potential in mitigating salinity stress. This study investigated the effectiveness of Se in alleviating salt stress in Carthamus tinctorius L. Two weeks old seedlings were exposed to NaCl and sodium selenate. Selenium application reduced the adverse effects of salinity on physiological, molecular, and biochemical processes compared to the control. Se treatment increased the proline and protein content in safflower under saline conditions. Furthermore, Se mitigated oxidative stress by enhancing the activities of POX and PPO in both leaf and root tissues. Se promoted the biosynthesis of secondary metabolites, leading to increases in total phenolic, flavonoids, and anthocyanin content under saline conditions. SOD and PAL genes expression increased in salinized C. tinctorius and treated with Se as a molecular strategy to cope with the salinity. The findings of this study elucidated some biochemical, physiological, and molecular mechanisms. These mechanisms underlie selenium-mediated salt resilience in C. tinctorius.

Keywords: Carthamus tinctorius L.; Antioxidant enzymes; Gene expression; NaCl; Oxidative stress; ROS.

MeSH terms

  • Carthamus tinctorius* / drug effects
  • Carthamus tinctorius* / genetics
  • Carthamus tinctorius* / metabolism
  • Carthamus tinctorius* / physiology
  • Gene Expression Regulation, Plant / drug effects
  • Oxidative Stress / drug effects
  • Plant Leaves / drug effects
  • Plant Leaves / metabolism
  • Plant Proteins / genetics
  • Plant Proteins / metabolism
  • Plant Roots / drug effects
  • Plant Roots / metabolism
  • Salinity
  • Salt Stress / drug effects
  • Salt Tolerance* / drug effects
  • Seedlings / drug effects
  • Seedlings / metabolism
  • Selenium* / pharmacology
  • Sodium Chloride / pharmacology

Substances

  • Selenium
  • Plant Proteins
  • Sodium Chloride