Descriptive Analysis of Ebola Virus Proteins

Virology. 1985 Nov;147(1):169-76. doi: 10.1016/0042-6822(85)90236-3.

Abstract

The virion proteins of two strains of Ebola virus were compared by SDS-polyacrylamide gel electrophoresis (PAGE) and radioimmunoprecipitation (RIP). Seven virion proteins were described; an L (180K), GP (125K), NP (104K), VP40 (40K), VP35 (35K), VP30 (30K), and VP24 (24K). The RNP complex of the virus contained the L, the NP, and VP30, with VP35 in loose association with them. The GP was the major spike protein, with VP40 and VP24 making up the remaining protein content of the multilayered envelope.

MeSH terms

  • Animals
  • Cell Line
  • Chlorocebus aethiops
  • Ebolavirus / analysis*
  • Electrophoresis, Polyacrylamide Gel
  • Kidney
  • Molecular Weight
  • Radioimmunoassay
  • Rhabdoviridae / analysis*
  • Species Specificity
  • Viral Proteins / analysis*
  • Virion / analysis*

Substances

  • Viral Proteins