Evaluation of the Patient Health Questionnaire (PHQ) Stress Scale over the course of the pandemic in a large German general population sample

J Affect Disord. 2025 Dec 1:390:119831. doi: 10.1016/j.jad.2025.119831. Epub 2025 Jul 5.

Abstract

Background: The Patient Health Questionnaire stress scale (PHQ stress) is a brief 10-item measure of psychosocial stressors, including work, health, relationship, and financial concerns. This study examines changes in psychosocial stress during the COVID-19 pandemic and evaluates the scale's temporal stability and measurement invariance.

Methods: Longitudinal population-based data (N = 4412) were collected at three time points during the pandemic (baseline, 4 months later, and 1.5 years after baseline). Internal consistency was assessed using McDonald's omega, and temporal stability via Pearson correlations. Confirmatory factor analysis (CFA) was conducted to verify the unidimensional factor structure. A sensitivity analysis included pre-pandemic data (1.5 years before baseline).

Results: PHQ stress scores increased across the four time points. Internal consistency remained acceptable (ω = 0.77-0.79), with moderate temporal stability (r = 0.631-0.697). CFA supported a stable one-factor structure (CFI = 0.947, TLI = 0.932, RMSEA = 0.048, SRMR = 0.047).

Conclusion: The PHQ stress scale demonstrated adequate reliability and temporal stability in a longitudinal context. It effectively captured variations in stress influenced by major external events such as the pandemic and economic inflation.

Keywords: Confirmatory factor analysis; Financial stress; Mental health trajectories; Pandemic stress; Patient health questionnaire; Psychological stress; Psychometrics.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • COVID-19* / psychology
  • Factor Analysis, Statistical
  • Female
  • Germany / epidemiology
  • Humans
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Pandemics
  • Patient Health Questionnaire* / standards
  • Psychometrics
  • Reproducibility of Results
  • SARS-CoV-2
  • Stress, Psychological* / diagnosis
  • Stress, Psychological* / psychology
  • Surveys and Questionnaires
  • Young Adult