Coronary artery anomalies are described as abnormal origin, course, or termination of any of the three main epicardial coronary arteries. They are generally not seen in cardiac complaints and are detected incidentally. However, some may be related to an increased risk of myocardial infarction, syncope, ventricular arrhythmias, and exercise-induced sudden cardiac death. Single coronary artery anomaly is very rare in coronary artery anomalies and provides a large myocardial perfusion area. Here we described an unusual very rare single coronary artery anomaly that the right coronary artery (RCA) originates from the middle left anterior descending coronary artery (LAD), presented with acute inferior myocardial infarction, and underwent LAD/RCA bifurcation stenting with the Culotte technique.