Pyoderma gangrenosum treated with cyclosporin A

Br J Dermatol. 1985 Nov;113(5):601-4. doi: 10.1111/j.1365-2133.1985.tb02385.x.


A 49-year-old woman with a 14-year history of pyoderma gangrenosum unresponsive to a variety of systemic and topical treatments was given oral cyclosporin A (CyA), a potent immunosuppressive agent widely used in organ transplantation for the prophylaxis of acute graft-versus-host disease. Improvement and subsequent healing of the lesions was evident within 3 weeks of starting treatment and has continued for the duration of treatment (12 months).

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cyclosporins / administration & dosage
  • Cyclosporins / therapeutic use*
  • Drug Administration Schedule
  • Female
  • Humans
  • Pyoderma / drug therapy*
  • Skin Ulcer / drug therapy*


  • Cyclosporins