Abstract
Three cases are presented on patients on an MAOI who developed a transient syndrome of myoclonus, hyperreflexia, jaw quivering, teeth chattering and diaphoresis after L-Tryptophan was added. Caution is advised when considering the addition of a serotonergic agent to MAOI's.
MeSH terms
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Adult
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Antidepressive Agents, Tricyclic / adverse effects
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Drug Interactions
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Drug Therapy, Combination
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Female
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Humans
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Hyperhidrosis / chemically induced*
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Male
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Middle Aged
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Monoamine Oxidase Inhibitors / adverse effects
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Myoclonus / chemically induced*
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Phenelzine / adverse effects*
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Reflex, Abnormal / chemically induced*
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Syndrome
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Tryptophan / adverse effects*
Substances
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Antidepressive Agents, Tricyclic
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Monoamine Oxidase Inhibitors
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Tryptophan
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Phenelzine