Comparative Analysis of Wear Resistance in 4D-Printed vs. 3D-Printed Dental Prosthetics

J Pharm Bioallied Sci. 2025 Jun;17(Suppl 2):S1574-S1576. doi: 10.4103/jpbs.jpbs_1814_24. Epub 2025 Jun 18.

Abstract

Background: Advancements in additive manufacturing, particularly 3D printing, have revolutionized the field of dental prosthetics. Recently, 4D printing, which incorporates time-responsive materials, has emerged as a potential game-changer. This study aims to compare the wear resistance of 3D-printed and 4D-printed dental prosthetics to evaluate the clinical applicability of these innovative technologies.

Materials and methods: Dental prosthetics were fabricated using both 3D printing (polyetheretherketone, PEEK) and 4D printing (shape-memory polymer composites). A total of 40 prosthetics (20 per group) were subjected to wear simulation using a chewing simulator with a load of 50 N at 1 Hz for 100,000 cycles. Surface roughness (Ra) and volumetric loss (mm≥) were measured pre- and post-simulation using 3D laser scanning and confocal microscopy. Statistical analysis was performed using an independent t-test to compare the mean wear resistance between the two groups.

Results: The 4D-printed prosthetics exhibited significantly lower volumetric loss (mean: 0.34 ± 0.08 mm≥) compared to the 3D-printed prosthetics (mean: 0.76 ± 0.12 mm≥, P < 0.01). Surface roughness analysis revealed a smaller increase in Ra for 4D-printed prosthetics (from 0.22 ± 0.03 μm to 0.28 ± 0.05 μm) compared to 3D-printed prosthetics (from 0.24 ± 0.04 μm to 0.41 ± 0.06 μm, P < 0.01).

Conclusion: The study demonstrates that 4D-printed dental prosthetics possess superior wear resistance compared to 3D-printed prosthetics, highlighting their potential for enhanced longevity and clinical performance in restorative dentistry. Future studies should focus on long-term in vivo evaluations and material optimization to further validate these findings.

Keywords: 3D printing; 4D printing; additive manufacturing; dental prosthetics; restorative dentistry; shape-memory polymers; wear resistance.