Tuberculosis in Turkiye: Epidemiological insights and recommendations for progress

Eur J Clin Microbiol Infect Dis. 2025 Oct;44(10):2323-2330. doi: 10.1007/s10096-025-05201-w. Epub 2025 Jul 15.

Abstract

Background: Tuberculosis (TB) remains a significant global public health challenge. We provide an overview of the current TB epidemiology in Turkey, highlighting key findings related to TB incidence, diagnostic challenges, and treatment outcomes.

Results: A gradual decline in TB incidence in Turkiye has been observed over recent years. In 2022, the TB incidence rate was 11.5 per 100,000, falling short of achieving WHO's target of a 50% reduction by 2025. The prevalence of multidrug-resistant TB (MDR-TB) is rising, particularly among foreign-born populations, and delays in diagnosing extrapulmonary TB forms, such as TB meningitis and spondylodiscitis, continue to hinder effective treatment.

Conclusion: We identify critical gaps in diagnostic tools, treatment adherence, and healthcare worker knowledge. We provide a set of comprehensive recommendations aimed at reducing TB incidence and improving treatment success, including the implementation of rapid molecular diagnostic tests, strengthening health policies for at-risk populations (such as migrants), improving healthcare worker education, and leveraging mobile health platforms to monitor treatment adherence.

Keywords: Diagnostics; Extrapulmonary tuberculosis; Healthcare disparities; Migrant health; Tuberculosis (TB).

Publication types

  • Review

MeSH terms

  • Antitubercular Agents / therapeutic use
  • Humans
  • Incidence
  • Mycobacterium tuberculosis / drug effects
  • Prevalence
  • Tuberculosis* / diagnosis
  • Tuberculosis* / drug therapy
  • Tuberculosis* / epidemiology
  • Tuberculosis, Multidrug-Resistant / diagnosis
  • Tuberculosis, Multidrug-Resistant / drug therapy
  • Tuberculosis, Multidrug-Resistant / epidemiology
  • Turkey / epidemiology

Substances

  • Antitubercular Agents