Surgical and Patient-Reported Outcomes of Fresh Frozen Homologous Costal Cartilage in Primary, Revision, and Functional Rhinoplasty

Plast Reconstr Surg. 2026 Jan 1;157(1):28e-37e. doi: 10.1097/PRS.0000000000012303. Epub 2025 Jul 8.

Abstract

Background: Modern techniques in structure rhinoplasty require cartilage for grafting. The optimal source of this cartilage is debated. Fresh frozen homologous costal cartilage (FFHCC) grafts are a promising source of cartilage; further investigation is needed into efficacy and safety. The purpose of this article is to review an extensive rhinoplasty experience using FFHCC in cosmetic and functional applications.

Methods: Retrospective review of one surgeon's experience performing 123 rhinoplasties using FFHCC grafts was performed. Outcomes were postoperative complications and patient-reported outcome measures (PROMs).

Results: The average follow-up time was 11.0 months (range, 1 to 44 months). Infection was noted in 3 patients (2.4%). Resorption was noted in 1 patient (0.8%). Analysis of PROMs was at last follow-up. Nasal Obstruction Symptom Evaluation scores showed mean improvement of -7.9 ± 8.1 ( P < 0.001). Twenty-Two Item Sinonasal Outcomes Test scores showed mean improvement of -18.9 ± 17.5 ( P < 0.001). Epworth Sleepiness Scale scores showed mean improvement of -4.8 ± 5.8 ( P < 0.001). The Standardized Cosmesis and Health Nasal Outcomes Survey revealed total, functional, and cosmetic scores with a mean improvement of -13.5 ± 11.1 ( P < 0.001), -5.1 ± 5.9 ( P < 0.001), -8.2 ± 7.3 ( P < 0.001).

Conclusions: FFHCC grafts provide a convenient and economical off-the-shelf solution for rhinoplasty. The findings of this study support the safety of FFHCC use and demonstrate positive improvement in PROMs across multiple domains.

MeSH terms

  • Adolescent
  • Adult
  • Costal Cartilage* / transplantation
  • Cryopreservation
  • Esthetics
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Patient Reported Outcome Measures*
  • Postoperative Complications / epidemiology
  • Postoperative Complications / etiology
  • Reoperation / methods
  • Retrospective Studies
  • Rhinoplasty* / adverse effects
  • Rhinoplasty* / methods
  • Transplantation, Homologous / methods
  • Treatment Outcome
  • Young Adult