Chronic pelvic pain (CPP) presents a diagnostic challenge in which neurologic evaluation often play a central role, especially in cases resistant to standard treatments. Multiple sclerosis, herniated disc, and pudendal neuropathy are commonly associated with pelvic pain, but central sensitization, small fiber neuropathy, and other peripheral neuropathies can frequently contribute to pain persistence and complexity. This review guides neurologists in the evaluation of CPP from an interdisciplinary approach, providing strategies for differential diagnosis, neurodiagnostic testing, and symptom management tailored to the neurologic underpinnings of pelvic pain.
Keywords: COPCs; CPP; Chronic overlapping pain syndromes; Chronic pain; Chronic pelvic pain; Complex pain; Neuropathic pain; Pelvic pain.
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