Is serum selenium a risk factor for cancer?

Med Oncol Tumor Pharmacother. 1985;2(3):157-63. doi: 10.1007/BF02934543.


A narrow band of counties extending along the southeastern Atlantic coast from Jacksonville, Florida to Charleston, South Carolina were found to have excessively high incidence rates for esophageal cancer in non-white males. White males in the same areas have a 30% higher incidence rate for lung cancer but only average incidence rates were found for non-white males. Selenium is considered to decrease cancer risk in the animal model. In this coastal region, a study of 130 cancer patients who developed a malignancy 2-12 years after baseline examination showed no dose response relationship between baseline serum selenium levels and risk of subsequent cancer.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • African Continental Ancestry Group
  • Esophageal Neoplasms / etiology*
  • European Continental Ancestry Group
  • Female
  • Geography
  • Georgia
  • Humans
  • Male
  • Neoplasms / epidemiology
  • Neoplasms / etiology*
  • Reference Values
  • Risk
  • Rural Population
  • Selenium / blood*
  • Sex Factors


  • Selenium