Abstract
We have described a 63-year-old man with elevated titers of cold agglutinins who was found to have malignant histiocytosis. Treatment with cytotoxic agents resulted in a rapid though temporary clinical response. Malignant histiocytosis should be considered in patients with unexplained cold agglutinin disease.
Publication types
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Case Reports
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Agglutinins / analysis
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Anemia, Hemolytic, Autoimmune / drug therapy
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Anemia, Hemolytic, Autoimmune / pathology*
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Bone Marrow / pathology
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Cryoglobulins
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Diagnosis, Differential
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Humans
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Lymph Nodes / pathology
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Lymphatic Diseases / drug therapy
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Lymphatic Diseases / pathology*
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Male
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Middle Aged
Substances
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Agglutinins
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Cryoglobulins
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cold agglutinins