Dominantly inherited ureteropelvic junction obstruction

Urology. 1985 Dec;26(6):568-71. doi: 10.1016/0090-4295(85)90363-2.

Abstract

We report on siblings from two families with unilateral ureteropelvic junction obstruction. HLA studies were undertaken and found to be a useful marker between affected members. We believe that incomplete penetrance with variable expression is the most probable mode of transmission of this disorder.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Child, Preschool
  • Female
  • Gene Expression Regulation
  • Gene Frequency
  • Genes, Dominant*
  • HLA Antigens / analysis
  • HLA Antigens / genetics
  • Humans
  • Hydronephrosis / genetics
  • Hydronephrosis / pathology
  • Kidney Pelvis* / pathology
  • Male
  • Pedigree
  • Ureteral Obstruction / genetics*
  • Ureteral Obstruction / pathology

Substances

  • HLA Antigens