Diffuse alveolar septal amyloidosis presenting with recurrent hemoptysis and medial dissection of pulmonary arteries

Am Rev Respir Dis. 1985 Dec;132(6):1368-70. doi: 10.1164/arrd.1985.132.6.1368.


An unusual case of recurrent hemoptysis in a 56-yr-old woman is presented. After all the usual investigations for hemoptysis, left lower lobectomy revealed medial dissection of small and medium-sized pulmonary arteries with evidence of amyloid deposition. The patient subsequently developed the clinical picture of diffuse alveolar septal amyloidosis in association with primary amyloidosis. Pulmonary artery dissection is briefly reviewed, and vascular amyloidosis is presented as the probable origin in this case.

Publication types

  • Case Reports

MeSH terms

  • Amyloidosis / complications
  • Amyloidosis / pathology*
  • Aortic Dissection / etiology*
  • Aortic Dissection / pathology
  • Biopsy
  • Female
  • Hemoptysis / etiology*
  • Humans
  • Lung / ultrastructure*
  • Lung Diseases / pathology*
  • Middle Aged
  • Pulmonary Artery*
  • Recurrence