Surgical and endoscopic interventions in the management of idiopathic achalasia

Michael A Scaffidi; Nauzer Forbes; Louis Huynh; Rishi Bansal; Nikko Gimpaya; Sandra McKeown; Christopher Teshima; Samir C Grover; Robert Bechara; Rishad Khan

doi:10.1002/14651858.CD015808

Surgical and endoscopic interventions in the management of idiopathic achalasia

Cochrane Database Syst Rev. 2025 Aug 1;8(8):CD015808. doi: 10.1002/14651858.CD015808.

Authors

Affiliations

¹ Division of Gastroenterology, St. Michael's Hospital, University of Toronto, Toronto, Canada.
² Department of Medicine, Queen's University, Kingston, Canada.
³ Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Canada.
⁴ Division of Gastroenterology, Department of Medicine, Queen's University, Kingston, Canada.
⁵ Queen's University Library, Queen's University, Kingston, Canada.
⁶ Department of Medicine, Division of Gastroenterology, St. Michael's Hospital, University of Toronto, Toronto, Canada.
⁷ Division of Gastroenterology, Queen's University, Kingston Health Sciences Center, Kingston, Canada.

Abstract

This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the benefits and harms of endoscopic and surgical interventions for idiopathic achalasia, including pneumatic dilation, laparoscopic Heller myotomy (LHM), and per-oral endoscopic myotomy (POEM), using pairwise meta-analyses for direct comparisons and network meta-analysis for integrating direct and indirect comparisons.

MeSH terms

Dilatation / methods
Esophageal Achalasia* / surgery
Esophageal Achalasia* / therapy
Esophagoscopy* / methods
Heller Myotomy / adverse effects
Heller Myotomy / methods
Humans
Laparoscopy / methods
Myotomy / methods
Network Meta-Analysis as Topic
Randomized Controlled Trials as Topic
Systematic Reviews as Topic