Tetra-amelia with multiple malformations in six male fetuses of one kindred

Eur J Pediatr. 1985 Nov;144(4):412-4. doi: 10.1007/BF00441792.

Abstract

An Arab Moslem kindred is reported in which six abnormal male fetuses were born in three closely related sibships. They had amelia, malformed head and other severe skeletal and visceral malformations. The similarities and differences between the developmental and inherent characteristics found in our patients and in families with Roberts syndrome are discussed.

Publication types

  • Case Reports

MeSH terms

  • Abnormalities, Multiple / genetics*
  • Adult
  • Chromosome Banding
  • Consanguinity
  • Ectromelia / genetics*
  • Female
  • Genes, Recessive
  • Genetic Linkage
  • Humans
  • Karyotyping
  • Male
  • Pedigree
  • Pregnancy
  • Syndrome
  • X Chromosome