Studies on WB-3559 A, B, C and D, new potent fibrinolytic agents. II. Structure elucidation and synthesis

J Antibiot (Tokyo). 1985 Nov;38(11):1476-86. doi: 10.7164/antibiotics.38.1476.

Abstract

The structures of WB-3559 A, B, C and D, new fibrinolytic agents isolated from Flavobacterium sp. No. 3559, have been elucidated to be as shown in 1, 2, 3 and 4, respectively, on the basis of chemical and spectroscopic evidence. Total synthesis of WB-3559 D (4) was achieved starting from the optically active aldehyde 14.

MeSH terms

  • Chemical Phenomena
  • Chemistry
  • Dipeptides* / chemical synthesis
  • Fibrinolytic Agents* / chemical synthesis
  • Gas Chromatography-Mass Spectrometry
  • Magnetic Resonance Spectroscopy

Substances

  • Dipeptides
  • Fibrinolytic Agents
  • WB 3559 B
  • WB 3559 A
  • WB 3559 D
  • WB 3559 C