Traumatic Hemorrhagic Lung Injury With Pelvic and Femur Fractures Requiring Resuscitative Balloon Occlusion of the Aorta, Operative Fixation on Dual-Circuit Venous Extracorporeal Membrane Oxygenation, and Systemic Isoflurane Sedation

Chest. 2025 Aug;168(2):e25-e28. doi: 10.1016/j.chest.2025.02.026.

Abstract

Traumatic pulmonary hemorrhage is uncommon and rarely results in respiratory failure requiring mechanical circulatory support. Indications for extracorporeal membrane oxygenation (ECMO) in injured patients are not well-defined, but recent work indicates a potential survival benefit. Additionally, coughing-induced hemorrhage requires a complex sedation strategy. We describe management of a young polytrauma patient with traumatic lung failure requiring advanced venovenous (VV)-ECMO support and novel sedation strategy to facilitate healing. An 18-year-old boy sustained a 40-foot fall and developed widespread traumatic hemorrhagic pneumatoceles leading to respiratory arrest, ultimately requiring parallel-circuit VV-ECMO support, as well as systemic isoflurane sedation achieved through the ECMO circuit. Orthopedic fixation was performed while on VV-ECMO. This young polytrauma patient had a primary traumatic pulmonary hemorrhagic process and orthopedic traumatic injuries that were successfully managed with parallel-circuit VV-ECMO and isoflurane sedation through the circuit.

Keywords: extracorporeal membrane oxygenation; hemorrhage; injuries; isoflurane; lung injury; trauma.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Anesthetics, Inhalation
  • Balloon Occlusion* / methods
  • Extracorporeal Membrane Oxygenation* / methods
  • Femoral Fractures* / complications
  • Femoral Fractures* / surgery
  • Hemorrhage* / etiology
  • Hemorrhage* / therapy
  • Humans
  • Isoflurane* / administration & dosage
  • Isoflurane* / therapeutic use
  • Lung Injury* / complications
  • Lung Injury* / etiology
  • Lung Injury* / therapy
  • Male
  • Multiple Trauma* / complications
  • Multiple Trauma* / therapy
  • Resuscitation / methods

Substances

  • Isoflurane
  • Anesthetics, Inhalation