Neonicotinoids such as acetamiprid are used extensively in veterinary medicine and agricultural practices. Acetamiprid has been reported to have effects on non-target organisms. This study investigates the effects of acetamiprid on common carp. Fish were exposed to 50 and 100 mg/L acetamiprid concentrations for 48 h and 96 h. Then, blood, gill and liver samples were taken from the fish. As a result of micronucleus analysis, it was determined that acetamiprid increased the number of micronuclei after 48 h of exposure at all concentrations 4-fold and after 96 h of exposure, at 50 mg/L concentration 2.5-fold and the 100 mg/L concentration 3-fold. According to the hematocrit values, a decrease was observed in the acetamiprid-exposure groups. While a small change was detected in AOPP and MDA values in gills and livers, histopathological analyses showed that 96 h exposure caused damage in both tissues. As a result, sublethal concentrations of acetamiprid caused toxic effects on common carp.
Keywords: Acetamiprid; Blood; Genotoxicity; Histopathology; MDA.
Copyright © 2025 Elsevier B.V. All rights reserved.