Effects of Withdrawal From Long-Term Nicotine Gum Use

Psychol Med. 1985 Nov;15(4):891-3. doi: 10.1017/s0033291700005134.


A small proportion of smokers who stop smoking with the aid of nicotine chewing gum continue to use the gum for more than a year. This study shows that when these people abstain from nicotine gum use they experience withdrawal symptoms similar to those found during cigarette withdrawal, including increased irritability, difficulty in concentrating and a drop in heart rate.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Chewing Gum / adverse effects*
  • Female
  • Heart Rate
  • Humans
  • Nicotine / adverse effects*
  • Substance Withdrawal Syndrome / etiology*


  • Chewing Gum
  • Nicotine