Clinical Impact of Neuropostural and Neuromuscular Optimization Protocols With Radio Electric Asymmetric Conveyer (REAC) Technology in Older Adults With Femoral Fractures: An Observational Study

Bruna Lombardi; Margherita Imbrenda; Valtere Giovannini; Vania Fontani; Salvatore Rinaldi

doi:10.7759/cureus.90221

Clinical Impact of Neuropostural and Neuromuscular Optimization Protocols With Radio Electric Asymmetric Conveyer (REAC) Technology in Older Adults With Femoral Fractures: An Observational Study

Cureus. 2025 Aug 16;17(8):e90221. doi: 10.7759/cureus.90221. eCollection 2025 Aug.

Authors

Bruna Lombardi¹, Margherita Imbrenda², Valtere Giovannini³, Vania Fontani^{4

5}, Salvatore Rinaldi^{4

5}

Affiliations

¹ Research Department, Rinaldi Fontani Foundation, Firenze, ITA.
² Physical and Rehabilitative Medicine Center, Azienda USL Toscana, Prato, ITA.
³ Physical Medicine and Rehabilitation, Casa di Cura Villa Fiorita, Prato, ITA.
⁴ Research Department, Rinaldi Fontani Foundation, Florence, ITA.
⁵ Department of Regenerative Medicine, Rinaldi Fontani Institute, Florence, ITA.

Abstract

Background: Femoral fractures in the elderly often result in long-lasting disability. Standard rehabilitation may fail to address neurofunctional alterations such as functional dysmetria (FD), which limit optimal motor recovery. This study evaluates the clinical utility of Radio Electric Asymmetric Conveyer (REAC) neuromodulation protocols, Neuro Postural Optimization (NPO) and Neuro Muscular Optimization (NMO), as adjuncts to standard rehabilitation in elderly patients post femoral fracture surgery.

Methods: This observational study was conducted at Casa di Cura Villa Fiorita (59100, Prato, Italy), within a clinical-scientific collaboration program with the Rinaldi Fontani Institute. Fourteen elderly patients (mean age 81.7 years) received one NPO session, followed by 10 NMO sessions in conjunction with standard physiotherapy. A matched historical control group (n = 14) received only conventional therapy. Assessed parameters included the Barthel Index (BI), Visual Analogue Scale (VAS) for pain, FD presence, and hospital length of stay. Statistical analysis used paired/unpaired t-tests (p < 0.05).

Results: FD was completely resolved in all REAC-treated patients following the single NPO session. This neurobiological modulation likely restores subcortical and cerebellar network homeostasis, enabling symmetrical motor output. The NMO protocol supported neuromotor pattern optimization throughout recovery. Compared to controls, the REAC group achieved significantly greater improvements in BI (+47.1 vs. +38.1 points, p = 0.006), pain reduction (-5.2 vs. -3.6, p < 0.001), and shorter hospital stay (-2.2 days, p = 0.027). No adverse effects were reported.

Conclusions: The integration of REAC NPO and NMO protocols into conventional rehabilitation enhanced motor symmetry, pain control, and recovery speed. These findings justify further randomized trials and suggest REAC neuromodulation as a valuable, non-invasive, and scalable strategy in orthopedic rehabilitation.

Keywords: femoral fractures; functional dysmetria; geriatric rehabilitation; neurobiological modulation; neuromuscular optimization; neuropostural optimization; non-invasive neuromodulation; pain reduction; postural symmetry; reac technology.