Acute osteomyelitis and arthritis, soft tissue infections as well as reactivated chronic osteomyelitis and septic total hip endoprostheses show positive scans in 111-In-Acetylaceton-Leucocyte-Scintigraphy. Negative results are found in chronic osteomyelitis and nonbacterial inflammations as rheumatic and degenerative diseases of the skeleton. Accuracy for all studies was 86%, specificity 100% and sensitivity 66%. False negative scans findings occurred especially in soft tissue infections and acute spondylitis. There have been no false positive scans. Typical case reports are illustrated.