Long-term follow-up of the effect of tympanic neurectomy on sialadenosis and recurrent parotitis

Acta Otolaryngol. 1985 Nov-Dec;100(5-6):437-43. doi: 10.3109/00016488509126568.


We examined the effect of tympanic neurectomy on the clinical symptoms and secretory function of the parotids in 13 patients with chronic parotitis or sialadenosis for 3 years. Each patient had significantly fewer complaints immediately after the surgery. In quite a few patients the improvement was transient only. Three years after neurectomy 3 of the 10 examined patients were free from complaints and 4 further patients had less severe complaints than before the surgery. Neurectomy was followed by a significant decrease in parotid flow rate and an increase in the sodium concentration of parotid saliva, while potassium concentration showed a slight decrease. Three years after the surgery the flow rate and the sodium concentration were moderately higher than before that. There was a significant, long-lasting change in the amylase activity of parotid saliva; 3 years after neurectomy it attained one-third of the preoperative value. A pharmacological test, carried out 3 years after neurectomy in 2 patients, suggested parasympathetic reinnervation of the parotid.

MeSH terms

  • Atropine / pharmacology
  • Ear, Middle / innervation*
  • Ear, Middle / surgery
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Parotitis / surgery*
  • Recurrence
  • Saliva / analysis
  • Saliva / enzymology
  • Salivary Gland Diseases / surgery*
  • Salivation / drug effects
  • Sialadenitis / surgery*
  • Tuberculosis / surgery*
  • Tuberculosis, Oral / surgery*


  • Atropine