AGA Clinical Practice Update on Management of Hepatitis Delta: Commentary

Gastroenterology. 2025 Oct;169(5):1063-1069. doi: 10.1053/j.gastro.2025.07.037. Epub 2025 Aug 20.

Abstract

Description: The purpose of this American Gastroenterological Association (AGA) Clinical Practice Update is to facilitate understanding and improve clinical management of patients with hepatitis delta virus infection.

Methods: This commentary was commissioned and approved by the AGA Institute Clinical Practice Updates Committee and the AGA Governing Board to provide timely guidance on a topic of high clinical importance to the AGA membership, and underwent internal peer review by the Clinical Practice Updates Committee and external peer review through standard procedures of Gastroenterology.

Keywords: Antivirals; Bulevirtide; Cirrhosis; Hepatitis Delta.

Publication types

  • Practice Guideline

MeSH terms

  • Antiviral Agents* / therapeutic use
  • Gastroenterology* / standards
  • Hepatitis D* / diagnosis
  • Hepatitis D* / drug therapy
  • Hepatitis D* / epidemiology
  • Hepatitis D* / therapy
  • Hepatitis Delta Virus / drug effects
  • Hepatitis Delta Virus / genetics
  • Humans
  • Societies, Medical
  • Treatment Outcome
  • United States

Substances

  • Antiviral Agents