[Use of Anti-Digoxin Antibodies in Digitalis Poisoning in an Infant]

Arch Fr Pediatr. 1985 Nov;42(9):803-4.
[Article in French]

Abstract

Digitalis poisoning is rare, always iatrogenic and potentially lethal in infants. We report one case of severe poisoning in which treatment with digoxin Fab antibody fragments was successful. Evolution of plasma digitoxin levels showed an initial rapid decrease (T 1/2:1 hour), then a slower decline (T 1/2:5.5 days). No undesirable side-effects were observed.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Antibodies / administration & dosage*
  • Digitoxin / poisoning*
  • Digoxin / immunology*
  • Female
  • Humans
  • Immunoglobulin Fab Fragments / administration & dosage
  • Infant, Newborn

Substances

  • Antibodies
  • Immunoglobulin Fab Fragments
  • Digoxin
  • Digitoxin