Allelic constitution of the hemoglobin beta chain in wild populations of the house mouse, Mus musculus

Biochem Genet. 1985 Dec;23(11-12):975-86. doi: 10.1007/BF00499941.


We studied the allelic frequency of the hemoglobin beta chain (Hbb) of wild mice, Mus musculus, collected from 46 localities, mostly in Asia and surrounding areas. The wild populations in the northern part of China, Korea, and the central part of Japan exhibited an almost monomorphic distribution of Hbbp. In the southern part of Asia, the frequency of Hbbp decreased and Hbbd was predominant. Although Hbbs and Hbbd are generally found in Europe, the Hbbp allele was present in Southeastern Europe (Bulgaria). In the light of these results, the Hbbp allele might have originated in mice of northern Asia.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles
  • Animal Population Groups / genetics*
  • Animals
  • Animals, Wild / blood
  • Animals, Wild / genetics*
  • Asia
  • Blood Protein Electrophoresis
  • Genetic Variation
  • Globins / genetics*
  • Mice / blood
  • Mice / genetics*
  • Species Specificity


  • Globins