Myelodysplastic Syndrome With Trisomy 8 and Behçet Disease-Like Intestinal and Upper Gastrointestinal Involvement

Yuzo Kawata; Kentaro Tominaga; Yusuke Kaneko; Saori Takashima; Yusuke Tani; Yuichi Kojima; Kazuya Takahashi; Shuji Terai

doi:10.1002/ccr3.70575

Myelodysplastic Syndrome With Trisomy 8 and Behçet Disease-Like Intestinal and Upper Gastrointestinal Involvement

Clin Case Rep. 2025 Aug 22;13(9):e70575. doi: 10.1002/ccr3.70575. eCollection 2025 Sep.

Authors

Yuzo Kawata¹, Kentaro Tominaga¹, Yusuke Kaneko¹, Saori Takashima², Yusuke Tani², Yuichi Kojima¹, Kazuya Takahashi¹, Shuji Terai¹

Affiliations

¹ Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences Niigata University Niigata Japan.
² Division of Molecular and Diagnostic Pathology Niigata University Graduate School of Medical and Dental Sciences Niigata Japan.

Abstract

We found an extremely rare case of upper gastrointestinal involvement in trisomy 8-positive myelodysplastic syndrome. This is the first reported case of trisomy 8-positive myelodysplastic syndrome with both upper and lower gastrointestinal involvement, which was successfully treated with bone marrow transplantation.

Keywords: Behçet's disease; bone marrow transplantation; gastrointestinal involvement; myelodysplastic syndrome; pseudo‐Pelger–Huet anomaly; trisomy 8.