Key highlights of the Japanese Society of Hypertension Guidelines for the management of elevated blood pressure and hypertension 2025 (JSH2025)

Hypertens Res. 2025 Oct;48(10):2500-2511. doi: 10.1038/s41440-025-02331-8. Epub 2025 Aug 29.

Abstract

Japan has long maintained a robust national health system with universal health coverage and accessible antihypertensive therapy. Nevertheless, population-level blood pressure (BP) control remains suboptimal. To address this public health challenge, the Japanese Society of Hypertension published the Guidelines for the Management of Elevated Blood Pressure and Hypertension 2025 (JSH2025), integrating evidence-based recommendations and practical approaches to improve hypertension care. JSH2025 introduces a dual-format structure comprising clinical question sections developed through systematic reviews and consensus-based narrative chapters. The key updates include universal BP targets of <130/80 mmHg across populations, promotion of home BP monitoring, stratified cardiovascular risk assessment, expanded guidance on digital health and behavioral interventions, and condition-specific management strategies for older adults, women, and cancer survivors. We outline the major updates and innovations in JSH2025 and show their clinical and public health implications.

Keywords: Clinical practice; Elevated blood pressure; Guidelines; Hypertension; Japanese Society of Hypertension.

Publication types

  • Editorial

MeSH terms

  • Antihypertensive Agents / therapeutic use
  • Blood Pressure
  • East Asian People
  • Humans
  • Hypertension* / drug therapy
  • Hypertension* / therapy
  • Japan
  • Practice Guidelines as Topic*
  • Societies, Medical

Substances

  • Antihypertensive Agents

Supplementary concepts

  • Japanese people