Industry 4.0 is driving innovation in cosmetics, with artificial intelligence (AI) playing a transformative role in modeling, prediction, and product design. This review explores the integration and current advances in emulsified cosmetic product design from a multiscale approach at molecular, microscopic, and macroscopic stages. Therefore, AI applications ranging from interfacial tension estimation to droplet size distribution modeling, cosmetic selection for skin suitability, and packaging design are discussed and explored to review the opportunity of encompassing in silico methodologies at the design stage of an emulsified cosmetic. As a result, this review identifies challenges and opportunities, emphasizing the transformative potential of AI integration in the cosmetics field, focusing on the opportunity to reduce experimental time and incorporate consumer-relevant formulations aiming to revolutionize the field.
© 2025 The Authors. Published by American Chemical Society.