[Will nanopores also sequence proteins ?]

Med Sci (Paris). 2025 Aug-Sep;41(8-9):703-705. doi: 10.1051/medsci/2025111. Epub 2025 Sep 8.
[Article in French]

Abstract

DNA sequencing using nanopores is now well established. Could the approach be extended to proteins ? There are a number of difficulties but work by many groups has shown proof-of-principle solutions for most of them. Further progress could indeed lead to a workable protein sequencing approach that would have many applications in research and in the clinic.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Humans
  • Nanopore Sequencing* / methods
  • Nanopores*
  • Nanotechnology* / methods
  • Nanotechnology* / trends
  • Proteins* / chemistry
  • Proteins* / genetics
  • Sequence Analysis, DNA / methods
  • Sequence Analysis, Protein* / methods
  • Sequence Analysis, Protein* / trends

Substances

  • Proteins