Zanubrutinib as Upfront Treatment in de Novo B-Cell Prolymphocytic Leukemia: The Case of Two Elderly Patients

Mediterr J Hematol Infect Dis. 2025 Sep 1;17(1):e2025061. doi: 10.4084/MJHID.2025.061. eCollection 2025.

Silvia Giorgi^{1

2}, Giovanna Leonardi², Monica Maccaferri², Elena Sbadili^{1

2}, Carlo Caterina^{1

2}, Giovanni Fera^{1

2}, Ambra Paolini³, Leonardo Potenza^{1

2}, Anna Candoni^{1

2}, Mario Luppi^{1

2}, Roberto Marasca^{1

2}

¹ Department of Oncology and Haematology, Haematology Division, University of Modena and Reggio Emilia, Modena, Italy.
² Hematology Unit, Dept of Oncology and Haematology, AOU di Modena, Policlinico Hospital, Modena, Italy.
³ Hematologic diagnostic unit, Department of laboratory diagnostics, AOU di Modena, Policlinico Hospital, Modena, Italy.

No abstract available

Keywords: B-cell prolymphocytic leukemia; Elderly; Orphan-drug disease; Zanubrutinib.