Reactive derivatives of benzo(a)pyrene and 7,12-dimethylbenz(a)anthracene cause S1 nuclease sensitive sites in DNA and "UV-like" repair

Biochem Biophys Res Commun. 1977 Jul 25;77(2):634-41. doi: 10.1016/s0006-291x(77)80026-0.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • 9,10-Dimethyl-1,2-benzanthracene / pharmacology*
  • Benz(a)Anthracenes / pharmacology*
  • Benzopyrenes / pharmacology*
  • Cell Survival / drug effects
  • Cells, Cultured
  • DNA / metabolism*
  • DNA Repair*
  • Epoxy Compounds / pharmacology
  • Fibroblasts / drug effects
  • Fibroblasts / metabolism
  • Fibroblasts / radiation effects
  • Humans
  • Methylnitronitrosoguanidine / pharmacology*
  • Ultraviolet Rays*
  • Xeroderma Pigmentosum / metabolism

Substances

  • Benz(a)Anthracenes
  • Benzopyrenes
  • Epoxy Compounds
  • Methylnitronitrosoguanidine
  • 9,10-Dimethyl-1,2-benzanthracene
  • DNA