Comparison of Current International Guidelines for the Management of Alopecia Areata-Comprehensive Review

Int J Mol Sci. 2025 Sep 4;26(17):8632. doi: 10.3390/ijms26178632.

Abstract

Alopecia areata is a persistent autoimmune-mediated disease with a complicated pathophysiology and a prevalence of approximately 2%. The exact pathogenesis is yet to be identified; nevertheless, environmental factors, autoimmune mechanisms and genetic factors among others all contribute to the multifactorial etiopathogenesis of the disease. Even though alopecia areata is frequently self-limiting and recovery can occur on its own, it can cause esthetic challenges that might precipitate psychosocial disorders. This article aims to provide a clinical update on alopecia areata comparing the most important international guidelines, with particular emphasis on current treatment options and comorbidities.

Keywords: alopecia areata; general dermatology; guidelines; medical dermatology; review.

Publication types

  • Review
  • Comparative Study

MeSH terms

  • Alopecia Areata* / epidemiology
  • Alopecia Areata* / etiology
  • Alopecia Areata* / therapy
  • Humans
  • Practice Guidelines as Topic*