Mass transfer in brain dialysis devices--a new method for the estimation of extracellular amino acids concentration

J Neurosci Methods. Nov-Dec 1985;15(3):263-8. doi: 10.1016/0165-0270(85)90107-4.


A simple mathematical description of mass transfer in brain dialysis devices is presented. The validity of this model is supported by results from both in vitro and in vivo dialysis experiments. Based on this description, an alternative approach for estimating the extracellular concentration of amino acids is outlined.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acids / analysis*
  • Animals
  • Body Fluid Compartments
  • Brain Chemistry*
  • Dialysis / methods*
  • Extracellular Space / analysis*
  • Mathematics
  • Models, Neurological
  • Olfactory Bulb / analysis
  • Rabbits


  • Amino Acids