Suppression of Rho-associated kinase 1 (ROCK1) promotes human hematopoietic stem cell expansion by attenuating mitochondrial fission

Leukemia. 2025 Nov;39(11):2825-2829. doi: 10.1038/s41375-025-02770-9. Epub 2025 Sep 16.

Xuepeng Wang^{1

2}, Baskar Ramdas³, Ramesh Kumar³, Ji Zhang^{3

4}, Reuben Kapur^{5

6}

¹ Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA. xuepwang@iu.edu.
² Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, IN, USA. xuepwang@iu.edu.
³ Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA.
⁴ Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, IN, USA.
⁵ Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA. rkapur@iupui.edu.
⁶ Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, IN, USA. rkapur@iupui.edu.

No abstract available

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