Towards AI-Based Strep Throat Detection and Interpretation for Remote Australian Indigenous Communities

Sensors (Basel). 2025 Sep 10;25(18):5636. doi: 10.3390/s25185636.

Abstract

Streptococcus pharyngitis (strep throat) poses a significant health challenge in rural and remote Indigenous communities in Australia, where access to medical resources is limited. Delays in diagnosis and treatment increase the risk of serious complications, including acute rheumatic fever and rheumatic heart disease. This paper presents a proof-of-concept AI-based diagnostic model designed to support clinicians in underserved communities. The model combines a lightweight Swin Transformer-based image classifier with a BLIP-2-based explainable image annotation system. The classifier predicts strep throat from throat images, while the explainable model enhances transparency by identifying key clinical features such as tonsillar swelling, erythema, and exudate, with synthetic labels generated using GPT-4o-mini. The classifier achieves 97.1% accuracy and an ROC-AUC of 0.993, with an inference time of 13.8 ms and a model size of 28 million parameters; these results demonstrate suitability for deployment in resource-constrained settings. As a proof-of-concept, this work illustrates the potential of AI-assisted diagnostics to improve healthcare access and could benefit similar research efforts that support clinical decision-making in remote and underserved regions.

Keywords: deep learning; large language model; strep throat detection and interpretation; transformer architecture; vision sensors.

MeSH terms

  • Artificial Intelligence*
  • Australia
  • Humans
  • Pharyngitis* / diagnosis
  • Pharyngitis* / microbiology
  • Pharynx / diagnostic imaging
  • Pharynx / microbiology
  • Rural Population
  • Streptococcal Infections* / diagnosis
  • Streptococcal Infections* / microbiology