Background and aims: Despite the long-term success of Roux-en-Y gastric bypass, dumping syndrome (DS) is one of its significant limitations. Our study aimed to review the effectiveness and safety of transoral outlet reduction (TORe) for DS.
Methods: From inception to May 2024, an individualized search strategy for major databases was developed. The primary and secondary outcomes of our interest were TORe's technical and clinical success rates, periprocedural adverse events, and reintervention rates.
Results: Four studies with 241 patients were included. The pooled technical success rate was 100% (CI 99.08%-100%). The pooled mean Sigstad score difference calculated before and after the procedure was 13.13 (CI 11.90-15.56; P < .01), reflecting clinical success. The pooled periprocedural adverse event rate was 10.46% (CI 0.42%-28.30%) and the pooled reintervention rate was 7.99% (CI 1.46%-18.05%).
Conclusions: Our study concludes that TORe is an effective and safe procedure for treating DS among patients who undergo Roux-en-Y gastric bypass.
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